As with any negotiation, pitch your opening offer low enough to give you room to manoeuvre. Decide what price you are prepared to go to, and any other key conditions which affect the value of the premises to you.
Find out as much as possible about the vendor's negotiating position. For example, whether the vendor is in a hurry to sell, and whether there have been any other offers.
Look for evidence supporting the case for a lower price. For example, there may be similar premises in the area being offered for less. Use any faults shown up in the survey as negotiating points. Highlight any weaknesses the premises have.
Unless you are a skilled negotiator, it's usually a good idea to negotiate through your advisers.